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Immunity and Diseases Scientific background to autoimmune diseases - page 8 / 22

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Organ specific Autoimmune Diseases

Hashimoto’s Thyroiditis

Frequently seen in middle aged women

X’terised by infiltration of thyroid gland by lymphocytes, macrophages and plasma cells

The ensuing inflammatory response causes GOITER or visible enlargement of thyroid gland – a physiological response to hypothyroidism (decreased production of thyroid hormones

Hypothyroidism is caused when Abs are formed to a number of thyroid proteins including thyroglobulin and thyroid peroxidase – both involved in iodine uptake

Autoimmune hemolytic anaemia

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