In the early 1900's, a bitter compound was found in the leaves of certain olive trees called "Oleuropein." This compound was determined to be part of the olive tree's powerful disease resistant structure. In 1962, an Italian researcher recorded that oleuropein had the ability to lower blood pressure in animals. Other European researchers validated that claim and also found it to increase blood flow in the coronary arteries, relieve arrhythmias and prevent intestinal muscle spasms. (b) The search began for the chemical agent within oleuropein that would be the most important medically. A Dutch researcher found it. The chemical was elenolic acid. Further European research determined this compound to have strong bacteriocidal capabilities as well. (c,d,k,l) (See listing under Viruses, Bacterias and Parasitic Protozoans)
In the late 60's and early 70's, The Upjohn Companies' test studies were published by The American Society for Microbiology (e) in regards to a new multifunctional monoterpene which they had isolated from various parts of the olive tree. The compound was called calcium elenolate, a crystalline salt form of elenolic acid. When they tested this compound it was found to be virucidal against all viruses for which it was tested. The compound acted effectively at low concentrations without any harmful influence on host cell mechanisms. It was also found to be extremely safe and nontoxic, even at high doses. While it worked extremely well in-vitro, it was unsuccessful in-vitro. When injected into the blood stream, the compound bound quickly to the blood serum protein and rendered itself ineffective. They were unable to overcome this problem and terminated their research. During this same period, other companies had interest in the compound and performed various tests, but also lost interest. (f,g) Then in 1990, interest was renewed and the process of bringing the remarkable product Olive Leaf Extractto market began.
Finally in 1995, through independent scientific research, success was achieved by East Park Research, Inc., opening the way for clinical application of this natural olive leaf extract and Olive Leaf Extract was born. This 100% natural product is classified as a food supplement and currently no other known herbal product in the history of the world is demonstrating itself to be as medicinally wide spectrum.
How It Works
According to laboratory tests, calcium elenolate (derived from oleuropein) kills viruses by interfering with certain amino acid production processes. This interference prevents virus shedding, budding or assembly at the cell membrane. Studies suggest that this compound has the ability to penetrate infected host cells and irreversibly inhibit viral replication. (e,g) In retroviruses, this compound neutralizes the production of the reverse transcriptase enzyme (f,g) and is believed to also neutralize the protease enzyme as well. These enzymes are essential for retroviruses such as HIV to alter the RNA of a healthy cell.
Researchers in Europe investigated the properties of oleuropein and suggested that it inactivated bacteria by dissolving the outer lining of the microbes. More recent studies (h,i) of oleuropein show that it seems to protect low density lipoprotein from oxidation, thus reducing the LDL (the bad cholesterol). Another research study in France remarks that Olea europaea leaf extracts show extremely high antioxidative qualities. (j)
The new Olive Leaf Extract extract not only confirms the earlier test finding (less the serum binding