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Table 2 Pharmacotherapy Classes and Mechanisms of Action

Selective Serotonin Reuptake Inhibitors (SSRIs) Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs)

Antidepressant

Brand Name(s)

Antidepressant

(Manufacturer)

Generic Name

Celexa (Forest Laboratories)

Citalopram

Lexapro (Forest Laboratories)

Escitalopram

Prozac/Serafem (Eli Lilly)

Fluoxetine

Luvox* (Solvay Pharmaceuticals)

Fluvoxamine

Paxil/Pexeva (Glaxo Smith Kline)/ (Synthon Pharmaceuticals)

Paroxetine

Zoloft (Pfizer)

Sertraline

Cymbalta (SNRI) (Eli Lilly)

Duloxetine

Effexor (SNRI) (Wyeth Pharmaceuticals)

Venlafaxine

Pristiq (SNRI) (Wyeth Pharmaceuticals)

Desvenlafaxine

*Original manufacturer noted. Currently available only in generic form.

Indications MDD

MDD GAD

MDD OCD Bulimia nervosa Panic Disorder PMDD

OCD SAD

MDD Panic Disorder SAD PMDD OCD GAD PTSD

MDD OCD Panic Disorder PTSD PMDD SAD

MDD GAD DPN

MDD GAD SAD PD

MDD

Depression

Notes

23

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