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PRIMARY AND SECONDARY PREVENTION OF CARDIOVASCULAR DISEASES - page 14 / 38

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Hypertension-Class 1

Prevalence

Increases with age (9% at age 19-24 years, 75 % age>75 years)

African Americans>Whites

Men>Women

Associated risk

The shape of the CVD risk curve with BP is linear

Increment of 20mmHg SBP or 10mmHg DBP doubles risk of CVD

Benefit of intervention

Many randomized trials confirmed the protective effect of treating mild to moderate HTN

10mmHg decrease in SBP, sustained of 10 years, prevents 1 CVD death in 10 people treated

ALLHAT demonstrated efficacy of thiazide diuretics compared with other agents

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