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PRIMARY AND SECONDARY PREVENTION OF CARDIOVASCULAR DISEASES - page 19 / 38

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Hypercholesterolema-Cost efficiency

Cost efficiency of non-pharmacological interventions is unclear

Pharmacological intervention is clearly cost-effective in secondary prevention

4-S Trial -$5,400/QALY for men, $10,500/QALY for women

Cost decreases as lipid levels increase

In primary prevention statins fail to reach a cost effective ratio (>$50,000/QALY)

Calculations are highly sensitive to drug cost

Hopefully drug costs will decrease in the future

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