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PRIMARY AND SECONDARY PREVENTION OF CARDIOVASCULAR DISEASES - page 21 / 38

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Hypercholesterolema-Treatment

Benefits of statins in addition to lipid lowering

Anti-proliferative effects

Anti-oxidant effects

Plaque-stabilizing effects

Change in lipid content of plaque

New NCEP guidelines-”Lower is better”

Lower LDL goal to <70mg/dl (CVD of equivalent)

Lower LDL goal to <100mg/dl (>2 risk factors)

There does not appear to be an LDL below which risk does not fall

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