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PRIMARY AND SECONDARY PREVENTION OF CARDIOVASCULAR DISEASES - page 24 / 38

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Antiplatlet Agents-Primary prevention

5 large primary prevention trials of low-dose ASA

Meta-analysis-small benefit in men

Concern regarding increased risk of hemorrhagic stroke

Data on women is limited

Breakpoint

Use low-dose ASA if 10-year risk of CVD is >6% in men

Ongoing Women’s Health Study addressing risk-benefit ratio in primary prevention

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