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PRIMARY AND SECONDARY PREVENTION OF CARDIOVASCULAR DISEASES - page 25 / 38

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Beta-blockers-Class 1

Many trials have demonstrated long-term efficacy of BB after MI in mortality reduction

About 25% reduction over long term

Many trials have also shown reduction in recurrent CVD events

Greater efficacy of BB with increased beta-blockade as assessed by heart rate reduction

BB effective in CHF, especially carvedilol

BB are highly cost-effective ($11,000/QALY)

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