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PRIMARY AND SECONDARY PREVENTION OF CARDIOVASCULAR DISEASES - page 34 / 38

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Postmenopausal estrogen therapy-Class 3

Meta-analyses of 40 cohort studies suggested a 50% reduction in CVD risk. This was true for primary and secondary prevention

Data from 7 randomized trials not only failed to support a benefit of hormone therapy, but actually demonstrated an increased CVD risk

HERS Trial (secondary prevention)-no CVD benefit

Hormone therapy is no longer recommended to prevent CVD

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