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PRIMARY AND SECONDARY PREVENTION OF CARDIOVASCULAR DISEASES - page 35 / 38

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Psychosocial factors-Class 3

Depression, chronic hostility, social isolation, lack of social support have been consistently linked with CVD

Data on intervention is limited and confounded by difficulty in measurement and inconsistent definitions

One meta-analysis of 37 studies demonstrated a 29% reduction in recurrent MI and 34% in total mortality with reduction in psychosocial stressors

SADHART and ENRICHD studies, pharmacologic treatment of depression after MI, reduced second MI rates, CHF, recurrent angina and CVD death rates  

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