X hits on this document

131 views

0 shares

0 downloads

0 comments

11 / 52

Insulin dependent diabetes mellitus

Spontaneous:  NOD mouse, BB rat

Induced:  Rat insulin promoter transgenics, thymectomy and sublethal irradiation in rats

Arthritis

Induced:  Collagen induced arthritis in rats and mice, adjuvant arthritis in mice

Systemic lupus erythematosus (glomerular nephritis)

Spontaneous:  NZBxNAW F1, NZBxSWR F1, MRL1pr

Induced:  Mercuric chloride in BN rats

Autoimmune thyroiditis

Spontaneous:  Obese strain chickens

Induced:  Experimental autoimmune thyroiditis in mice

Alkylosing spondylitis

Induced:  HLA-B27 transgenic rats

Inflammatory bowel disease

Spontaneous:  IL-2, IL-10, TCR-  chain knock-out mice, SCID mice restored with CD4+ Tcell subsets

Induced:  Haptenated colonic proteins in mice, proteoglycans in Lewis rats

Multiple sclerosis

Induced:  experimental allergic encephalomyelitis in a variety of laboratory animals

Animal models

Document info
Document views131
Page views131
Page last viewedFri Dec 09 13:51:05 UTC 2016
Pages52
Paragraphs639
Words2051

Comments