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Systemic sclerosis

Systemic connective tissue disease

Essential vasomotor disturbances; fibrosis; subsequent atrophy of the skin, subcutaneous tissue, muscles, and internal organs

Raynaud´s phenomenon

Major features include centrally located skin sclerosis that affects the arms, face, and/or neck.

Minor features include sclerodactyly, erosions, atrophia of the fingertips, and bilateral lung fibrosis.

SSc is diagnosed when a patient has 1 major and 2 minor criteria.

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