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Vitamin E can alter the efficacy of anticoagulant or anticonvulsant drugs.

Vitamin E increase bleeding time in patient taking herbal preparations as Feverfew or Gingko Biloba.

Inorganic iron supplements destroy vitamin E, so individuals taking iron supplements should space out their doses (e.g., iron in the morning and vitamin E in the evening).

Large doses of vitamin A can decrease the absorption of vitamin E.

Alcohol and mineral oil can also reduce vitamin E absorption, and these substances should be avoided in vitamin E deficient individuals.

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