Health Canada Advisory Statement Recommendations
z 1. IGRA may be performed in TST-positive, immunocompetent adults who are at relatively low risk of being infected with TB (including casual contacts) and of progressing to active disease if infected. Persons with a positive IGRA result may be considered for treatment of LTBI.
z 2. For close contacts or those individuals who have high or increased risk of progression to active disease if infected, a TST (or both TST and IGRA) should be used, and if either is positive the contact should be considered to have LTBI.
z 3. If both TST and IGRA testing will be used, it is recommended that blood be drawn for IGRA before or on the same day as placing the TST.