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New Diagnostics in Tuberculosis: Interferon - page 35 / 38

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35 / 38

Study, Year

Country

IGRA

Participants

Days When Tested

Change or Difference†

Pathan, 2001

United Kingdom

Elispot

active TB

0 and 30–240

Decrease

Carrara, 2004

Italy

Elispot

18 active TB

0, 90,180

Decrease (13/18 reverted to neg)

Aiken, 2006

Gambia

Elispot

active TB

0, 365

Decrease (36% reverted)

Ewer, 2006

United Kingdom

Elispot

LTBI

0, 180, 365, 640

Decrease, 6/38 (16%) reverted with Rx, 7/14 (50%) reverted without Rx

Wilkinson, 2006

United Kingdom

Elispot

LTBI

0, 26, 82

No change

Pai, 2006

India

QFT-IT

LTBI

0, 365, 640

No change

Changes in IGRAs Results With Therapy

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