X hits on this document

18 views

0 shares

0 downloads

0 comments

4 / 7

MARIJUANA (p.4)

  • 8.

    Pharmacological Effects (cont.)

    • b.

      in humans

CNS effects – perception of senses being enhanced time distortion (time duration is overestimated) increased sense of well-being, mild euphoria relaxation, usually reduced anxiety, sedation reduced RTs, reduced motor skills, poor coordination dissociation of ideas, deceased ability to focus decreased attention, decreased STM decreased cognitive function (reduced learn/memory) rare hallucinations (often visual)

at high doses – acute depression, panic reactions, mild paranoia

long-term, chronic use:

  • -

    some tolerance develops to motor effects & to cognitive effects

  • -

    but still show impairment of information-processing skills

  • -

    esp. cannot filter out irrelevant stimuli

  • -

    decreased spatial skills

  • -

    decreased ability to “map” the environment

  • -

    poor organizing skills, e.g. poor routines of daily living

  • -

    S feels out of control, alientated, life lacts focus/meaning

(part of the “amotivational syndrome”?)

  • -

    note: above all show improvement when d/c drug

back to baseline?...

addiction: Is MJ addicting? THC does --- increased release of DA in reward/attentional focus brain areas (basal ganglia, nucl. Accumbens, prefrontal cortex) & maybe increases activity at the mu opioid RS (ventral tegmentum) --- so concern re. dependency is warranted, based on CNS mechanisms…

Document info
Document views18
Page views18
Page last viewedFri Dec 09 08:20:14 UTC 2016
Pages7
Paragraphs84
Words1067

Comments