Gerontological Nursing – 2 credit undergraduate course Page 6 of 20
Week 3: Polypharmacy
Learning objectives: Identify the demographics of medication usage in older adults Define polypharmacy and describe related provider/client characteristics Identify normal anatomical, physiological, & functional changes of aging, as related to drug absorption, distribution, and clearance Describe adverse reactions to medications commonly occurring in older adults Identify iatrogenic problems associated with multi-geriatric syndromes and their mediation regimens Discuss strategies for preventing polypharmacy and enhancing medication compliance/adherence Develop an understanding of the complex cost issues related to medications for older adults Discuss effects of tricyclic antidepressant drugs in older adults
Gerontologic Nursing, 2nd edition – Chapter 21: Pharmacologic Management
Gray, S.L., Sager, M., Lestico, M.R., & Jalaluddin, M. (1998). Adverse drug events in hospitalized elderly, The Journals of Gerontology, 53A(1), M59-M63.
Owens, N.J., Silliman, R.A., & Fretwell., M.D. (1989). The relationship between comprehensive functional assessment and optimal pharmacotherapy in the older patient, DICP, The Annals of Pharmacotherapy, 23, 847-853.
Flaherty, J.H., Perry, H.M., Lynchard, G.S., & Morley, J.E. (2000). Polypharmacy and hospitalization among older home care patients. The Journals of Gerontology, 55A(10), M554-M559.
Hanlon, J.T., Shimp, L.A., & Semla, T.P. (2000). Recent advances in geriatrics: drug-related problems in the elderly. The Annals of Pharmacotherapy, 24, 360- 365. (see Tables)
Medication usage in older adults
#s of prescriptions, economic implications
Definition of polypharmacy
Factors that lead to polypharmacy
Brief overview of normal age-related physiologic changes and effects on drug absorption, distribution, clearance (covered in greater detail in NURS 309)
Adverse reactions to medications commonly occurring in older adults
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