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Treatment of Schizophrenia (and Related Psychotic Disorders) - page 46 / 56

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Long-acting injectable (depot) antipsychotics

Until late 2003, only haloperidol and fluphenazine available in the U.S.

Long-acting risperidone introduced late 2003

Injections approximately every 2 weeks (fluphenazine and risperidone) or 4 weeks (haloperidol)

Goal is to decrease “noncompliance” and thus relapse--widely used but less commonly in last 10 years

Not yet clear if long-acting risperidone will reverse the trend

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