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PBC and PSC

PBC: Natural History and Prognosis

symptomatic PBC patients

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independent predictors of poor prognosis

advanced age

bilirubin level (>10 portends 2 year avg. survival)

poor synthetic function

hepatomegaly

ascites or edema

variceal bleed

advanced biopsy stage

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prognostic models have been developed and validated http://www.mayoclinic.org/gi-rst/mayomodel2.html

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