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PBC and PSC

Primary Sclerosing Cholangitis

most common type of sclerosing cholangitis in U.S.

autoimmune disease of the biliary tree

chronic inflammation and fibrosis of the bile ducts

may occur in association with other diseases (IBD, scleroderma, SLE, sprue…)

but lacks a specific etiology (AIDS infections, parasites, operative injury, cystic fibrosis, RPC…)

no cure

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