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PBC and PSC

PSC: Natural History and Prognosis

malabsorption

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steatorrhea

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calcium malabsorption and osteoporosis

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fat-soluble vitamin deficiencies

portal hypertension

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bleeding

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ascites

cholangiocarcinoma

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median survival of 5 months

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diagnosed in 3-20% of patients

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found in 30-40% of PSC patients at autopsy

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found in 23-33% of PSC patients at transplant

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tumor markers unproven as screening tools

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