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Anti-thyroid Drugs Adverse Effects

z Agranulocytosis – usually develops in the first

two months of therapy z Sore throat and fever may be the earliest indications

  • patients should be instructed to report these

immediately z Because it develops rapidly, periodic blood counts cannot guarantee early detection

z Hypothyroidism – if given in high doses; temporary administration of thyroid hormone may be required

z Enters breast milk and is contraindicated for nursing mothers

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