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Antigenic Structure and Function Research Update

Identification of Epitopes in the F and G Envelope Glycoproteins of RSV Involved in Receptor Binding and Eliciting a Protective Immune Response

Identified Linear Domains within F and G that bind to cells, inhibit virus infection, and block virus attachment to cells (Crim RL, et al., J Virol, 2007, 81:261)

Mapped cell binding domains on pre-fusion model of RSV-F

Studies being extended to identify epitopes recognized during human RSV infection

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