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Influenza Pathogenesis and Immunity Research Update

Contribution of NA-specific Immunity to Influenza Vaccine Efficacy

Develop practical assays to measure functional NA-specific antibody titers

Sandbulte et al. A miniaturized assay for influenza neuraminidase inhibiting antibodies utilizing reverse genetics-derived antigens. Influenza and other Respiratory Viruses 3: 233-240, 2009

Hassantoufighi et al. A Practical Influenza Neutralization Assay to Simultaneously Quantify Hemagglutinin and Neuraminidase-Inhibiting Antibody Responses. Vaccine 28:790-797, 2010

Evaluate role of NA-specific antibodies/inhibitors in selection of escape variants

Memoli  et al. Rapid selection of a transmissible multi-drug resistant influenza A/H3N2 virus in an immunocompromised host. J Inf Dis, in press.

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