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2126

CANCER

November 15, 2007 / Volume 110 / Number 10

TABLE 2 (continued)

Joinpoint analyses (1975–2004)a

(Delay-adjusted)

1975–1983

Leukemia

1975–2004

(Delay-adjusted)

1975–2004

Urinary bladder

1975–2004

(Delay-adjusted)

1975–2004

Cervix uteri

1975–1981

(Delay-adjusted)

1975–1981

Thyroid

1975–1977

(Delay-adjusted)

1975–1977

Pancreas

1975–1983

Kidney and renal pelvis

(Delay-adjusted) Oral cavity and pharynx

(Delay-adjusted) Stomach

(Delay-adjusted)

1975–2004 1975–2004 1975–1980 1975–1980 1975–2004 1975–2004

Sex/cancer site or type

Years

Trend 1

Trend 2

Trend 3

APCd

Years

APCd

Years

APCd

5.3 5.3 0.2 0.1

1.1 1.1

e e

1.0 1.0

e e

e e

1977–1980 1977–1980 1983–2004 1983–2004

e e e e e e e e e e e

1981–1996 1981–1996

1980–2004 1980–2004

3.9

e

3.7

e

6.5 6.5 1.4 1.3

  • 0.1

0.2 0.1 0.2

  • 4.6

  • 4.6

2.2 2.3 2.7 2.6

  • 1.6

  • 1.6

1980–1995 1980–1995

1996–2004 1996–2004

    • 2.3

      e

    • 2.3

      e

Trend 4

5.9

e

6.1

e

Years

1995–2004 1995–2004

APCd

Source: Surveillance, Epidemiology, and End Results (SEER) 9 areas covering about 10% of the U.S. population (Connecticut, Hawaii, Iowa, Utah, and New Mexico and the metropolitan areas of San Francisco, Detroit, Atlanta, and Seattle-Puget Sound). APC indicates annual percent change; NOS, not otherwise specified. Joinpoint analyses with up to 3 joinpoints are based on rates per 100,000 persons and were age-adjusted to the 2000 U.S. standard population (19 age groups, Census p25–1130; Jointpoint [JP] Regression Pro- gram, Version 3.0; National Cancer Institute, April, 2005). All sites excludes myelodysplastic syndromes and borderline tumors; ovary excludes borderline tumors. The top 15 cancers were selected based on the sex-specific, age-adjusted incidence rates for 2000–2004 for all races combined and are listed in rank order. APC is based on rates that were age-adjusted to the 2000 U.S. standard population (19 age groups; Census, p25–1130). APC is statistically significantly different from zero (2-sided P <.05). a b c d e

uterus. Lung cancer death rates have increased since 1975. However, the rate of increase has slowed over time to 0.2% annually from 1995 to 2004. Finally, from 2001 through 2004, liver cancer rates increased 2.6% annually in women.

Cancer Incidence Rates, 20002004 and Fixed Interval Trends, 19952004 Table 4 presents cancer incidence for the 15 most common cancers for each sex, for all races/ethnici- ties combined, and for the 6 major race/ethnic populations. In men, the 3 leading incident cancers were prostate, lung, and colon and rectum in all race/ethnic populations, although colorectal cancer ranked second and lung cancer ranked third among Hispanic men. For most men, bladder cancer and NHL were the fourth and fifth leading incident can- cers. However, cancers of the kidney and bladder ranked fourth and fifth for black and AI/AN men, and liver and stomach ranked fourth and fifth for API men.

Cancer incidence trends for men in all race/eth- nic groups combined decreased from 1995 through

2004. Among men, incidence rates of cancers of the lung, larynx, and stomach decreased in each race/ ethnic population for which the APC was presented. Prostate cancer rates decreased for black and AI/AN men but were stable for white, API, Hispanic, and non-Hispanic men. Colorectal cancer incidence rates decreased for white, API, and non-Hispanic men and remained stable for black, AI/AN, and His- panic men. Increases were noted for kidney and liver cancer in men except API and AI/AN men, in whom the rates remained stable. Thyroid cancer showed the largest annual increases in populations for which the APC was presented. Melanoma rates increased in white and non-Hispanic men, were stable in API and Hispanic men, and decreased in black men.

Among women, the 4 leading incident cancers from 2000 through 2004 were breast, lung, colon and rectum, and uterus across all race/ethnic popula- tions (Table 4). NHL was ranked fifth for all popula- tions except black, API, and AI/AN women. Cancer of the pancreas ranked fifth for black women, thyr- oid cancer ranked fifth for API women, and kidney

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