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Clevidipine Phase III Studies: Perioperative Hypertension - page 23 / 65

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ECLIPSE SNP: Drug Administration (Safety Population)

Aronson S et al. Anesth Analg 2008 (in press)

Clevidipine

N=296

SNP

N=283

Initiated Pre-op n (%)

52 (17.6)

34 (12.0)

Initiated Intra-op n (%)

161 (54.4)

158 (55.8)

Initiated Post-op n (%)

83 (28.0)

90 (31.8)

Dosed During Pre-op n (%)

52 (17.6)

34 (12.0)

Dosed During Intra-op n (%)

209 (70.6)

185 (65.4)

Dosed During Post-op n (%)

219 (74.0)

204 (72.1)

Overall Infusion Duration including periods when infusion stopped (Median)

6.7 h

5.4 h

Average Infusion Rate (Median)

6.4 mL/hr

8.5 mL/hr

Total Infusion Volume (Median)

26.5 mL

25.6 mL

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