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Clevidipine Phase III Studies: Perioperative Hypertension - page 36 / 65

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Post-Hoc Logistic Regression Results: Predictors of Mortality

P-Value

Odds Ratio

95% CI

[Lower Limit, Upper Limit]

Surgery Duration (hour)

<0.0001

1.517

[1.240, 1.856]

Age (year)

0.0003

1.070

[1.031, 1.110]

Pre-op Creatinine ≥ 1.2 mg/dL

0.0031

2.670

[1.392, 5.122]

AUC (1 mm Hg * min)

0.0069

1.003

[1.001, 1.004]

Additional surgical procedures

0.0089

2.409

[1.246, 4.655]

Pre-op Hgb (g/dL)

0.0135

0.824

[0.707, 0.961]

Pre-op SBP >160 or DBP > 105 mm Hg

0.0228

2.386

[1.147, 4.963]

History of COPD

0.0228

2.326

[1.125, 4.812]

History of recent MI (<6 months prior)

0.0312

2.197

[1.073, 4.497]

Aronson S et al. American College of Cardiology 56th Annual Scientific Session. March 2007. New Orleans, LA

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