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Clevidipine Phase III Studies: Perioperative Hypertension - page 56 / 65

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VELOCITY: Primary Outcome Measures

88.9% of patients (ITT) achieved prespecified TR within 30 min

Only 2.6% of patients failed to reach TR during or after initial 30 min treatment period.

2 patients (1.6%) fell below the lower TR limit within first 3 min

One patient had narrower than specified TR (205-195 mm Hg), SBP was 15 mm Hg below the lower limit

One patient exceeded the lower SBP limit (160 mm Hg) by 4 mm Hg

Both patients continued clevidipine infusion beyond 18 hours without AEs

No hypotensive events were reported

Annals of Emergency Medicine - 06 June 2008 (10.1016/j.annemergmed.2008.04.025)

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