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Clevidipine Phase III Studies: Perioperative Hypertension - page 59 / 65

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VELOCITY: Secondary Outcome Measures

Median time to first achievement of Target Range (TR) was 10.9 min (95% CI 9.0-15.0)

Median percentage decrease in SBP necessary to achieve upper limit of TR was 14.2%

Median time for patients to achieve 15% reduction in SBP was 9.5 min

Mean decrease in SBP of 21.1% at 30 min

Among all patients who achieved their SBP TR within or past the 30 min period (n=112), the average mean infusion rate to achieve TR was 5.71 + 4.9 mg/hr

Median percentage increase in pulse rate did not exceed 13.2% (10 bpm) at any point during the first 30 min period

Pulse rate continued to remain stable during 18 hrs of continuous clevidipine infusion

Annals of Emergency Medicine - 06 June 2008 (10.1016/j.annemergmed.2008.04.025)

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