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Clevidipine Phase III Studies: Perioperative Hypertension - page 6 / 65

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ESCAPE-1

ESCAPE-2

Clevidipine

n=53

Placebo

N=52

Clevidipine

N=61

Placebo

N=49

Age, mean (yr)

65

61.7*

63.8

62.3

Age > 65 (%)

62.3

34.6*

54.1

34.7*

Male (%)

69.8

69.2

77

77.6

Stroke (%)

5.7

3.8

6.6

8.2

Hx HTN (%)

100

100

83.6

83.7

Diabetes(%)

35.8

48.1

34.4

34.7

Previous MI (%)

30.2

11.5*

24.6

30.6

Previous CABG (%)

9.4

1.9

1.6

4.1

Angina Pectoris (%)

64.2

57.7

42.6

63.3*

Previous MI (%)

30.2

11.5*

24.6

30.6

Baseline preoperative SBP (mm Hg),  mean

182

177

147.4

150.5

ESCAPE Results:  Demographics

Levy JH et al. Anesth Analg. 2007;105:918-925

Singla N et al. Anesth Analg. 2008;107:59-67

* p<0.05

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