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California Science Teachers Association In collaboration with the California Department of Education - page 38 / 50





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COURSE CONCEPTIntegrated Science 4 focuses on the collection of evidence that underlies the development of scientific ideas and how science supports the development of various technologies. The sequence emphasizes literature-based research, hands-on investigations, and problem-solving to support student understanding of scientific knowledge and process. Students should discover through reading, research, and problem-solving the underlying concepts supporting technology and how technology can be used to help provide for a sustainable future. Student research should include two essential questions: How is it that scientists know what they know about a particular topic, and how does this knowledge help to develop technology that extends our ability to change the world?

The instructional environment for Integrated Science 4 is intended to be student centered. Students explore each* of the eleven topics through a series of required investigations and other labs as needed. The investigations are guided by key questions that focus on the science and technological implications of each topic. The explorations allow them to examine key ideas through hands-on activities and to participate in the scientific process by designing their own experiments and building their own equipment. Each topic lends itself to directed instruction so that students become aware of major scientific issues and social implications in each topic. Students are expected to choose a project** based on one or more of the standards, to research the science embedded in the task, and to present their findings to the class at the end of each semester.

Semester 1—Human body systems

The human body is studied from a systems perspective spanning molecular interactions within the cell to the relationships among organs. Students examine the molecular machinery common to living organisms and apply this understanding to improving the quality of life. At the macro level the complexity of the human body is investigated with a particular focus on vision. Internal feedback loops that help our bodies survive stressful and changing environmental conditions are examined at the cellular and organ levels.

Topic Replication

Standards B5a, C2h*, B5b

Key Questions How can we design a machine to efficiently and accurately make DNA?


B10a, B10b, B10c, B10d, B10e, B10f* B9c, B9h*

What is the process of making a vaccine?

Human Body Systems

What is the relationship between the nervous, endocrine and muscular systems?

Required Investigation Students replicate a short nucleotide sequence and insert it into bacteria and test for its presence. Students investigate the process of perfecting an antibiotic. Students will investigate the factors influencing the activity of enzymes such as catalase and diastase.


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