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Mechanism of Phagocytosis

  • Microbes adhere to the phagocyte

    • More efficient when complement proteins or antibodies coat the foreign microbe

  • Pseudopods engulf the particle (antigen) into a phagosome

  • Phagosomes fuse with a lysosome to form a phagolysosome

  • Invaders in the phagolysosome are digested by proteolytic enzymes

  • Indigestible and residual material is removed by exocytosis

Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings

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