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Inflammation Response: Vasodilation & Increased Vascular Permeability

  • Begins with a flood of inflammatory chemicals

released into the extracellular fluid

  • Inflammatory mediators:

    • Kinins, prostaglandins (PGs), complement, and cytokines

    • Released by injured tissue, phagocytes, lymphocytes, and mast cells

    • Cause local small blood vessels to dilate, resulting in hyperemia

Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings

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