Inflammatory Response: Phagocytic Mobilization
Four main phases (cont.):
Diapedesis – neutrophils leave the capillary (emigration)
Chemotaxis – inflammatory chemicals act as chemotactic agents. Neutrophils follow chemicals to source upon which they destroy foreign materials found there.
Monocytes follow the neutrophils, swell in size and develop lysosomes and become macrophages and replace the neutrophils.
Macrophages remain at the site removing debris during prolonged chronic inflammation.
The goal is to remove pathogens, dead or damaged cells, debris so that the tissue can be repaired