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MHC Proteins

  • Are coded for by MHC genes and are unique to an individual

  • Each MHC molecule displays a peptide, which is a normal cellular product of protein recycling

  • In infected cells, MHC Class I proteins bind to fragments of foreign antigens from within the infected cell, which play a crucial role in mobilizing the immune system

  • Peptides displayed by MHC Class II come from outside the cell

Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings

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