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Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings - page 43 / 62

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Lymphocytes

  • Immature lymphocytes released from bone marrow are essentially identical

  • Whether a lymphocyte matures into a B cell or a T cell depends on where in the body it becomes immunocompetent, e.g. becomes capable of recognizing its one specific antigen by binding to it (immunocompetance)

    • B cells mature in the bone marrow

    • T cells mature in the thymus

  • Each lymphocyte must be unresponsive to self-antigens

(self tolerance)

Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings

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