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Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings - page 48 / 62

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Immunocompetent B or T cells

  • Display a unique type of receptor that recognizes and binds to a single specific antigen

  • Become immunocompetent before they encounter antigens they may later attack

  • Are exported to secondary lymphoid tissue where encounters with antigens occur

  • Mature into fully functional antigen-activated cells upon binding with their recognized antigen

  • It is genes, not antigens, that determine immune cell antigen receptor

  • Antigen determines which T cell or B cell will proliferate and mount an attack

  • Most immunocompetent cells remain idle (over 1 billion different antigen receptors)

Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings

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