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Phagocytes

  • Pathogens that penetrate the skin & mucosae into the underlying connective tissue confront phagocytes

  • Macrophages are the chief phagocytic cells

    • Derived brom monocytes that leave the bloodstream, enter tissue and develop into macrophages

  • Free macrophages wander throughout a region in search of cellular debris

  • Kupffer cells (liver) and microglia (brain) are fixed

macrophages

Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings

Figure 21.2a

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