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139th National Cancer Advisory Board

TABLE OF CONTENTS

WEDNESDAY, SEPTEMBER 6, 2006

IV. V.

Questions and Answers ......................................................................................... President’s Cancer Panel—Dr. LaSalle Leffall, Jr....................................................... Legislative Update—Ms. Susan Erickson ...................................................................

VI.

Questions and Answers ......................................................................................... American Society for Clinical Oncology Report—Dr. Gabriel N. Hortobagyi...........

VII.

Questions and Answers ......................................................................................... NCI Community-based Cancer Centers Pilot Program—Dr. John Niederhuber.........

VIII.

Questions and Answers ......................................................................................... Update: Human Cancer Genome Atlas Project—Dr. Anna Barker ............................

IX.

Questions and Answers ......................................................................................... Tamoxifen and STAR Trial Results—Drs. Leslie Ford and Larry Wickerham ..........

X.

Questions and Answers ......................................................................................... Adolescent and Young Adult Oncology Report—Ms. Cheri Nichols and Drs. Barry

I. II. III.

XI.

XII.

Call to Order, Opening Remarks, and Approval of Minutes—Dr. Carolyn D. Runowicz .............. 1

THURSDAY, SEPTEMBER 7, 2006

Javed Khan, David Wink, and Steven K. Libutti .................................................................... 23 Introduction—Dr. Robert Wiltrout.......................................................................................... 24 Influence of Immunogenetic Variation on HIV Disease—Dr. Mary Carrington .................... 25 Questions and Answers ........................................................................................................... 26 Microarrays and Artificial Intelligence for Diagnosis, Prognosis, and Selection of Therapeutic Targets in Cancer—Dr. Javed Khan ............................................................. 26 Research Program of the Redox Faculty—Dr. David Wink ................................................... 27 The Trans-NIH Angiogenesis Research Program—Dr. Steven K. Libutti ............................. 29 Closed Session—Dr. Carolyn D. Runowicz .................................................................................. 31

Future Board Meeting Dates—Dr. Carolyn D. Runowicz........................................... NCI Director’s Report—Dr. John Niederhuber...........................................................

.................... 1 .................... 1 .................... 4 .................... 5 .................... 6 .................... 7 .................... 7 .................. 11 .................. 11 .................. 13 .................. 13 .................. 16 .................. 17 .................. 20 Anderson,

K a r e n A l b r i t t o n , a n d M i c h a e l C a l i g i u r 21 i . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Questions and Answers ........................................................................................................... 23 Scientific Update: Center for Cancer Research—Drs. Robert Wiltrout, Mary Carrington,

  • XIII.

    NCI Cancer Centers Director’s Report—Drs. John Mendelsohn and Martin D. Abeloff ............. 31 Questions and Answers ........................................................................................................... 34

  • XIV.

    Report of the Workshop To Review the NCI’s Rapid Access to Intervention Development (RAID) Program—Drs. Joseph E. Tomaszewski, John Mendelsohn, and James Doroshow ............................................................................................................... 35 Questions and Answers ........................................................................................................... 38

  • XV.

    Progress Report: NCI Innovative Molecular Analysis Technology (IMAT) Program— Drs. Anna Barker, Gregory Downing, Stephen J. Kron, and Jan E. Schnitzer ....................... 38 Introduction—Dr. Anna Barker .............................................................................................. 38 IMAT Program Overview—Dr. Gregory Downing................................................................ 39 Developing Tests for Bcr-Abl Activity and Gleevec® Resistance in CML Patients— Dr. Stephen J. Kron........................................................................................................... 40 IMAT Facilities Technology Exploration To Advance Clinical Translation—Dr. Jan E. Schnitzer ........................................................................................................................... 41

iii

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