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«laboratory analyzers buyers guide

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Average Length of System Startup Time and Daily Maintenance: 5 minutes

Beckman Coulter Inc. 200 S. Kraemer Blvd. Brea, CA 92822 Contact: Daniel Siegenthaler Market Manger Telephone: (714) 961-3594 Fax: (714) 961-3825 dmsiegenthaler@beckman.com www.beckmancoulter.com Primary Product: UniCel® DxC 800 Synchron® Clinical System; UniCel DxC 600 Synchron Clinical System Methodologies Used: ISE, conductivity, glucose oxygen sensor, photometric, colorimetric, turbidimetric, near infrared particle immunoassay Tests Available in the U.S.: More than 100 tests, including general care chemistries, critical care chemistries, urine chemistries, esoteric chemistries, CSF chemistries, protein/ serology, TDMs, DATs and thyroids Throughput: DxC 800: 1,440 tests/hour; DxC 600: 990 tests/hour Time to First Result: Stat analysis in less than one minute; analyze 11 critical care chemistries in 42 seconds Sample Size: 3-69 mL Frequency of Calibration: Varies Integrated Data Management: Yes Open Reagent System: Yes Primary Tube Sampling: Yes Positive Sample ID: Yes Onboard Dilution: Yes Other Utility Requirements: Deionized water What differentiates your product from other products on the market? Closed-tube sampling technology; ability to analyze 11 critical care chemistries in just 42 seconds; proactive remote diagnostics (weekly analysis of instrument trends to prevent technical problems from occurring); centrifugable racks; clot detection; serum indices; automation connectability; continuous autoloader; polychromatic correction; near infrared

particle immunoassay detection system Operational Type: Random access; batch; stat Separation Methodologies: Centrifugation Sample Handling System: Rack Number of Reagent Containers Onboard/Tests/Container: 65/70 up to 400 tests per container (photometric); up to 3,200 tests per container (modular) Reagents Refrigerated Onboard: Yes Walkaway Capacity in Specimen/Tests Assays: Up to one hour System Liquid or Dry: Liquid Average Length of System Startup Time and Daily Maintenance: None Contact: Leslie Cutter Product Manager Telephone: (714) 993-8432 Fax: (714) 961-3825 lccutter@beckman.com www.beckmancoulter.com Primary Product: IMMAGE 800® Immunochemistry System Methodologies Used: Rate Nephelometry, Rate Inhibition Nephelometry, Rate Near Infrared Particle Immunoassay (NIPIA), Rate NIPIA Inhibition. Gold Standard in Protein testing. Rate Nephelometry methods collect hundreds of datapoint readings for each assay being measured to ensure accurate, reliable results. Tests Available in the U.S.: IgG, Urine IgG, IgA, IgM, IgALC, IgMLC, Kappa, Lambda, C3, C4, RF, ASO, CRP, hsCRP, Haptoglobin, Beta 2 Microglobulin*, IgE, Albumin, Prealbumin, Ferritin, Transferrin, Apolipoprotein A1, Apolipoprotein B, Lipoprotein (a), Microalbumin, Alpha1 Microglobulin, Alpha 1 Acid Glycoprotein, Cerluoplasmin, Alpha 1 Antitrypsin, Alpha 2 Macroglobulin, Properdin Factor B, DNB, Antithrombin, Digoxin, Carbamazepine, Phenytoin, Phenobarbital, Valproic Acid, Gentamicin, Tobramycin, free Kappa Light chains*, free Lambda chains*, IgG subclasses*. Note: * UDR assay Throughput: 180 tests/hour Time to First Result: 6.5 minutes Sample Size: Assay dependent: 6-40 uL

Frequency of Calibration: 30 days; within lot calibration available Integrated Data Management: Yes Open Reagent System: Yes Primary Tube Sampling: Yes Positive Sample ID: Yes Onboard Dilution: Yes Other Utility Requirements: 115 VAC RMS What differentiates your product from other products on the market? True Rate Nephelometry methodology, onboard antigen excess checking for 14 assays and dynamic blanking Operational Type: Continuous random access Sample Handling System: Rack Number of Reagent Containers Onboard/Tests/Container: 24 cartridges/300 tests per cartridge Reagents Refrigerated Onboard: 15 degrees, cooled reagent compartment Walkaway Capacity in Specimen/Tests Assays: Continuous loading, diluent capacity for 1,440 tests System Liquid or Dry: Liquid Average Length of System Startup Time and Daily Maintenance: <1 minute Contact: Mark Watanabe Product Manager Telephone: (714) 961-3779 Fax: (714) 961-3825 mswatanabe@beckman.com www.beckmancoulter.com Primary Product: UniCel® DxC 600i Type of Analyzer: Chemistry/immunoassay/data management/automation system Methodologies Used: Near-infrared particle immuno, turbidimetric, ISE, conductivity, oxygen sensor, photometric, chemiluminescent Tests Available in the U.S.: Approximately 150 tests. Immunoassay: thyroid, fertility, anemia, cardiovascular, adrenal/pituitary, specialty, tumor markers, infectious disease and skeletal tests; Chemistry: general, critical care, urine, esoteric, proteins/serologies, TDMs, DATs

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Throughput: Chemistry: 990/hour; Immunoassay: 100/hour Time to First Result: Varies; less than or equal to two minutes Sample Size: 2-69 mL Frequency of Calibration: Varies Integrated Data Management: Yes Open Reagent System: No Primary Tube Sampling: Yes Positive Sample ID: Yes Onboard Dilution: Yes Other Utility Requirements: Deionized water What differentiates your product from other products on the market? Consolidates chemistry and immunoassay testing on a single platform; parallel processing technology allows both immunoassay and chemistry testing to be performed simultaneously; closed-tube sampling for chemistry tests allows lab technologists to load sample tubes on the instrument without decapping them, which improves efficiency and helps reduce exposure to biohazards and repetitive motion injuries; closed-tube aliquotting, in which the instrument automatically makes a daughter tube from a primary tube for immunoassay testing; serum indices and clot detection features improved integrity of patient test results; data management system allows technologists to program chemistry and immunoassay tests from a single computer interface Operational Type: Continuous random access, batch and stat Separation Methodologies: Centrifugation, homogenous Sample Handling System: Rack Number of Reagent Containers Onboard/Tests/Container: 89 onboard reagents; 25-400 tests per container (photometric); up to 3,200 tests per container (modular) Reagents Refrigerated Onboard: Yes Walkaway Capacity in Specimen/Tests Assays: One hour System Liquid or Dry: Liquid

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