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List of Tables

Table I-1. Summary of Various Types of Thresholds ..................................................... 13 Table II-1. Signs and Symptoms of Allergic Reactions to Food ..................................... 18 Table II-2. Allergy Prevalence in the United States ........................................................ 19 Table III-1. Estimated Daily Gluten Consumption from Combinations of

Different Amounts of Food Containing Different Levels of Gluten ........................ 40 Table IV-1. Approaches to Establishing Thresholds ....................................................... 42 Table IV-2. General Criteria for Evaluating and Selecting Recommended

Approaches to Establish Thresholds......................................................................... 46 Table IV-3. Specific Criteria for Evaluating Analytical Methods for Food

Allergens ................................................................................................................... 49 Table IV-4. Specific Criteria for Evaluating Allergen Oral Challenge Studies .............. 51 Table IV-5. Summary of Published LOAELs for Food Allergens .................................. 54 Table IV-6. Example of Uncertainty Factors for the Safety Assessment-Based

Approach Using Peanuts........................................................................................... 55 Table IV-7. Specific Criteria for Evaluating Protein in Oil Studies................................ 57 Table IV-8. Specific Criteria for Evaluating Gluten Analytical Methods....................... 59 Table IV-9. Specific Criteria for Evaluating Gluten Oral Challenge Studies................... 60 Table IV-10. Example of Uncertainty Factors for the Safety Assessment-Based

Approach................................................................................................................... 64

Revised Threshold Report

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