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Study

Published

Test Population

Food Allergen Tested

Test Material

Lowest Dose Tested (mg

Dose Progression

Hazelnut Fish

Ground

proteina)

Bernhisel- Broadbent et al., 1992b

Yes

11 fish allergic children and adults

Raw and cooked extracts of 9 species

Not reported

Not reported

Caffarelli et al., 1995

Yes

21 infants and children with no previous egg exposure, 14 reacted

Egg

Dried egg

0.042

Not reported

Appendix 2: Evaluation of Available Allergen Oral Challenge Studies.

Magnolfi et al., 1996

Yes

131 skin prick positive children, 8 reacted

Soy

“1 drop” for infants

6 defined doses

88 mg soy protein for older children

7 defined doses

Formula

Responses at lowest dose tested?

LOAEL Observed (mg proteina, b)

Sign(s)s or symptom(s) used to determine LOAEL

Population Dose/Response Data

No

2775

Objective Not reported

No No

Not reported

Not reported

No

No

0.42

Objective

No

360

Objective

No

Yes

88

Objective

No

Revised Threshold Report

Page 91 of 108

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