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94 / 108

Mackerel

Not

Not reported

Not

500mg of

reported

reported

fish

Herring

Not

Not reported

Not

5mg of

reported

reported

fish

Population Dose/Response Data

Bindslev- Jensen and Mortz in Taylor et al., 2002

No

Bindslev- Jensen and Norgaard in Taylor et al., 2002

No

Sign(s)s or symptom(s) used to determine LOAEL

Study

Published

Test Population

Food Allergen Tested

Test Material

Lowest Dose Tested (mg proteina)

Dose Progression

Responses at lowest dose tested?

LOAEL Observed (mg proteina, b)

Bindslev- Jensen and Hansen in Taylor et al., 2002

No

14 patients, not clear whether all were challenged with each fish

Fish

Cod

Not reported

Not reported

5 mg of fish

Plaice

Not

Not reported

Not

6000mg

reported

reported

of fish

Ground

Not

Not reported

Not

40

3 milk allergic, 7 egg allergic patients

Milk

Whole

Not reported

Not reported

Not reported

180

Not reported

No

Egg

Whole raw

Not reported

Not reported

Not reported

0.65

Not reported

No

Appendix 2: Evaluation of Available Allergen Oral Challenge Studies.

5 patients

Peanut

reported

reported

Not reported

No

Revised Threshold Report

Page 94 of 108

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