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Study

Published

Test Population

Food Allergen Tested

Test Material

Lowest Dose Tested (mg proteina)

Dose Progression

Responses at lowest dose tested?

LOAEL Observed (mg proteina, b)

Sign(s)s or symptom(s) used to determine LOAEL

Population Dose/Response Data

“National Jewish” in Taylor et al., 2002

No

3 peanut allergic patients

Peanut

Ground

Not reported

Not reported

Not reported

2

Not reported

No

Rance in Taylor et al., 2002

No

74 peanut allergic, 31 milk allergic, 38 egg allergic, 6 fish allergic patients

Peanut

Ground

Not reported

Not reported

Not reported

0.25

Not reported

No

Milk

Whole

Not reported

Not reported

Not reported

15

Not reported

No

Egg

Whole raw

Not reported

Not reported

Not reported

0.13

Not reported

No

Fish

Minced

Not reported

Not reported

Not reported

16mg of fish

Not reported

No

Milk

Formula

Not reported

Not reported

Not reported

1.5

Not reported

No

Appendix 2: Evaluation of Available Allergen Oral Challenge Studies.

56 milk allergic patients

Zeiger in Taylor et al., 2002

No

Wensing et al., 2002a

Yes

31 hazelnut allergic adults

Hazelnut

Raw nuts

1

7 specified doses

Yes

1

Subjective and Objective

Yes

Revised Threshold Report

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