History of Microbiology Man kind has always been affected by diseases which were originally believed to be visitations by the gods and meant to punish evil doers. Hippocratus, father of medicine, observed that ill health resulted due to changes in air, winds, water, climate, food, nature of soil and habits of people. Varro (117-26 BC)said a theory that disease was caused by animated particles invisible to naked eye but which were carried in the air through the mouth and nose into the body. Fracastorius (1500 G.C.) proposed that the agents of communicable disease were living germs, that could be transmitted by direct contact with humans and animals, and indirectly by objects ; but no proof because of lacking experimental evidence.
Antony Van Leeuwenhoek (1632-1723 G.C.), father of Microbiology, observed “animalcules” using simple microscope with one lens. He was the first who properly described the different shapes of bacteria. Although Leeuwenhoek was not concerned about the origin of micro-organism; many other scientists were searching for an explanation for spontaneous appearance of living things from decaying meat, stagnating ponds, fermenting grains and infected wounds. On the bases of this observation, two major theories were formulated.
Theory of Abiogenesis
Theory of Biogenesis