in the gut to stimulate vomiting center in the central nervous system. It is superantigen causing staphylococcal food poisoning . Toxic shock syndrome toxin- Superantigen desquamative toxin Produced by S.aureus and Causes fever, shock, multiple-organ failure and skin rash.
. Exfoliative toxin-Epidermolytic superantigen S.aureus and uses generalized desquamation (staphylococcal scalded skin syndrome).
produced by of the skin
Epidermolytic toxin A: Chromosomal gene product and heat stable Epidermolytic toxin B: Plamid mediated and heat labile . Leukocidin: S aureus toxin which kills WBCs by forming pores and incresing cation permeability
Clinical features: . Folliculitis:Infection of one hair follicle. . Curbuncle: Infection of multiple hair follicle and surrounding skin. . Cellulitis: Infection of skin and subcutankeous tissue. . Abscess formation: focal suppuration . Mastitis: Infection of breast, especially in lactating mother . Bulous impetigo: Crusted superficial skin lesion . Pneumonia: Infection of lung parenchyma. . Empyema: Accumulation of pus in pleural space . Osteomyelitis: Infection of bone .Endocarditis and meningitis: Infection of heart tissue and leptomeninges respectively. . Food poisoning: Caused by enterotoxin produced by S.aureus