Opa (Protein II) . Important for attachement of bacteria to host cells. RMP (Protein III): Reduction-modifiable protein . It is associated with por in the formation of pores in the cell. Lipooligosaccharide(LOS): epithelial cells Toxicity in gonococcal infection is largely gue to the endotoxic effects of LOS 6. LiP(H8): Gonococcal surface exposed Heat-Modifiable like Opa Fbp(Iron binding protein):Expressed when there is limited available iron supply IgA1 protease:Splits and inactivates major mucosal IgA(IgA1) Clinical manifestation: Route of infection: Sexual contact Male: 3. 4. Responsible damage 5. to 7. 8.
. Gonococcal urethritis If complicated: Urethral stricture Gonococcal epididymitis Gonococcal epididymo-orchitis Infertility . Gonococcal suppurative arthritis
. Gonococcal cervicitis . Gonococcal salpingitis If compicated: Gonococcal tubo-ovarian abscess