Pelvic peritonitis Infertility Infant (When delivered through the infected birth canal) . Gonococcal ophthalmia neonatorum If untreated and complicated leads to blindness Laboratory diagnosis: Specimen: Urethral swab, cervical swab, eye swab Smear: Gram-negative intracellular diplococci More than five polymorphs per high power field.
Culture: Requires an enriched media like chocolate agar or thayer-martin agar. . Grows best in CO2 enriched aerobic atmosphere with optimal temperature of 35-37Oc. .Fastidious- Dies with exposure to sunlight, room temperature and drying. . Small glistening colonies. .Culture of urethral exudate from men are not necessary when the gram stain is positive but culture should be done for women Biochemical reaction: .Oxidase positive.
Ferment only glucose in carbohydrate utilization test
Serology: Antibodies to gonococcal pili and Omps can be Detected by immunoblotting, RIA or ELISA tests
Treatment: Gonorrhoea is difficult to treat because of resistance to lots of antibiotics, especially in developing countries.