Laboratory diagnosis: Specimen: Stool Microscopy: Typical ‘gull-wing’ shaped gram-negative rods. Typical darting motility of the bacteria under dark field microscopy or phase contrast microscopy Culture: Grow best at 420c on selective media but can be cultured at 37 oc. Watery and spreading or round and convex colonies on solid media at low oxygen tension.
Biochemica;l reaction: C jejuni ……………….. hydrolyzes hippurate. C. coli ……………… does not hydrolyze hippurate. Treatment: Erythromycin Shorten the duration of fecal shedding of bacteria
Helicobacter pylori General characteristics: . Spiral-shaped gram negative, motile rods with polar flagella Antigenic structure: Pili Protease Urease Pathogenesis and clinical features: Route of entry: Ingestion of contaminated food and drinks Familial clustering of H. pylori infection occurs . Type B chronic antral gastritis . Peptic ulcer disease (gastric and duodenal ulcer) microaerophilic,