mouth.There may be syphilitic meningitis,
nephritis, periostitis, hepatitis and retinitis. Primary and secondary syphilis are rich in spirochete from the site of the lesion and patients are highly infectious. Latent stage: Patients are symptom-free but relapse ca occur. Giagnosis is by serological test. Early latent stage: Relapse of symptoms and signs occur, and patients are infectious. It occurs with in 2 years of developing primary syphilis. Late latent stage: There is no relapse of symptoms and signs. Patients are not infectious. It occurs after 2 years of developing primary syphilis. Tertiary stage: Manifesting with gumma(granulomatous lesion) in bone, skin and liver; meningovascular syphilis, syphilitic paresis, tabes dorsalis, syphilitic aortitis and
Out come of acquired syphilis in untreated cases
One third of cases seems spontaneously cured during primary and secondary syphilis but no clear evidence
One third of cases become positive for serological tests of syphilis.
One third of cases develop tertiary syphilis.